Scientific Papers

The following is the list of peer reviewed publication and other publically-available non peer-reviewed documents that have been published about Mesoamerican Nephropathy and CKDu. It is intended to help individuals interested in reading what has been published in recent years. The list is updated from time-to-time


  1. Hansson E, Wegman DH, Wesseling C, Glaser J, Schlader ZJ, Wijkström J, Jakobsson K. Markers of kidney tubular and interstitial injury and function among sugarcane workers with cross-harvest serum creatinine elevation. Occup Environ Med. 2021 Dec 31:oemed-2021-107989. doi: 10.1136/oemed-2021-107989. Epub ahead of print. PMID: 34972693.

  2. Miller AC, Tuiz E, Shaw L, Flood D, Garcia P, Dhaenens E, Thomson DR, Barnoya J, Montano CM, Rohloff P. (2021). Population estimates of Glomerular Filtration Rate and Risk Factors for Chronic Kidney Disease in Guatemala, Kidney International Reports. doi: https://

  3. Fischer RSB, Unrine JM, Vangala C, Sanderson WT, Mandayam S, Murray KO (2020) Evidence of nickel and other trace elements and their relationship to clinical findings in acute Mesoamerican Nephropathy: A case-control analysis. PLoS ONE 15(11): e0240988.
  1. Hamilton, S.A., Nakanga, W.P., Prynn, J.E. et al. (2020). Prevalence and risk factors for chronic kidney disease of unknown cause in Malawi: a cross-sectional analysis in a rural and urban population. BMC Nephrol 21, 387.
  1. Pablo Garcia, Carlos Mendoza, Joaquin Barnoya, Jose Monzón, Ann C. Miller, Angie Aguilar-González, Julio Boj, Allan Cifuentes, Pedro Dávila, David Flood, Carolina Guzmán-Quilo, Agualuz Hernandez, Randall Lou-Meda, Eduardo Palacios, Vicente Sánchez-Polo, Regina Sosa, Peter Rohloff. (2020). CKD Care and Research in Guatemala: Overview and Meeting Report. Kidney International Reports, Volume 5, Issue 9, Pages 1567-1575.
  1. Glaser J, Hansson E, Weiss I, et al. (2020). Preventing kidney injury among sugarcane workers: promising evidence from enhanced workplace interventions. Occupational and Environmental Medicine;77:527-534.
  1. Sanchez Polo V, Garcia-Trabanino R, Rodriguez G, Madero M. (2020) Mesoamerican Nephropathy (MeN): What We Know so Far. Int J Nephrol Renovasc Dis.13:261-272. doi:10.2147/IJNRD.S270709
  1. Hansson, Erik; Glaser, Jason; Jakobsson, Kristina; Weiss, Ilana; Wesseling, Catarina; Lucas, Rebekah A.I.; Wei, Jason L.K.; Ekström, Ulf; Wijkström, Julia; Bodin, Theo; Johnson, Richard J.; Wegman, David H. (2020). “Pathophysiological Mechanisms by which Heat Stress Potentially Induces Kidney Inflammation and Chronic Kidney Disease in Sugarcane Workers” Nutrients 12, no. 6: 1639.
  1. Ferguson R., Leatherman S., Fiore M., Minnings K., Mosco M., Kaufman J., Kerns E., Amador JJ., Brooks D, Fiore M, Parekh R.S., Fiore L. (2020). Prevalence and Risk Factors for CKD in the General Population of Southwestern Nicaragua. JASN, 31 (7) 1585-1593; DOI: 10.1681/ASN.2019050521
  1. De Broe Marc, Vervaet Bejamin A. (2020). Is an Environmental Nephrotoxin the Primary Cause of CKDu (Mesoamerican Nephropathy)? PRO. Kidney360, 1 (7) 591-595; DOI: 10.34067/KID.0003172020
  1. Wesseling I. (2020). Is an environmental nephrotoxin the primary cause of CKDu (Mesoamerican nephropathy)? CON. Kidney360; doi:10.34067/KID.0002922020 
  1. Abeyagunawardena, A.S., Shroff, R. (2020). CKDu: the known unknowns. Pediatr Nephrol.
  1. Chapman, C. L., Johnson B.D., et al. (2020). “Hyperthermia and dehydration during physical work in the heat both contribute to the risk of acute kidney injury.” J Appl Physiol (1985).
  1. Haas, M. (2020). “The pathologist’s view.” Kidney International 97(5): 1060.  DOI: 
  1. Madero M., (2020). Is an Environmental Nephrotoxin the Primary Cause of CKDu (Mesoamerican Nephropathy)? Commentary. Kidney360, 1 (7) 602-603; DOI: 10.34067/KID.0003412020 
  1. Senanayake, S.,  Gunawardena  N., et al. (2020). “Health related quality of life in chronic kidney disease; a descriptive study in a rural Sri Lankan community affected by chronic kidney disease.” Health Qual Life Outcomes 18(1): 106.
  1. Vervaet, B. A., Nast C. C., et al. (2020). “Chronic interstitial nephritis in agricultural communities is a toxin-induced proximal tubular nephropathy.” Kidney Int 97(2): 350-369.
  1. Leibler, J.H., Ramirez-Rubio, O., Velázquez, J.J.A. et al. (2020). Biomarkers of kidney injury among children in a high-risk region for chronic kidney disease of uncertain etiology. Pediatr Nephrol.
  1. Petropoulos Z.E., Laws R. L., Amador J.J., López-Pilarte D., Kaufman J., Weiner D, Ramirez-Rubio O, Brooks D., McClean M., Scammell M. (2020). Kidney Function, Self-Reported Symptoms, and Urine Findings in Nicaraguan Sugarcane Workers. Kidney360, 1 (10) 1042-1051; DOI: 10.34067/KID.0003392020
  1. Wesseling, C., Glaser J., et al. (2020). “Chronic kidney disease of non-traditional origin in Mesoamerica: a disease primarily driven by occupational heat stress.” Rev Panam Salud Publica 44: e15. DOI: 10.26633 / RPSP.2020.15
  1. Ruiz-Alejos AO, Caplin B, Miranda JJ, Pearce N, Bernabé-Ortiz A. (2020). CKD and CKDu in Northern Peru: a cross-sectional analysis under the DEGREE protocol. Research Square. DOI: 10.21203/
  1. Krisher L, Butler-Dawson J, Yoder H, et al. (2020). Electrolyte Beverage Intake to Promote Hydration and Maintain Kidney Function in Guatemalan Sugarcane Workers Laboring in Hot Conditions. J Occup Environ Med.;62(12):e696-e703. doi:10.1097/JOM.0000000000002033
  1. García Pablo, Sánchez-Polo Vicente. Global dialysis perspective: Guatemala. (2020). Kidney360; doi:10.34067/KID.0004092020 
  1. Sorensen CJ, Krisher L, Butler-Dawson J, Dally M, Dexter L, Asensio C, Cruz A, Newman LS. Workplace Screening Identifies Clinically Significant and Potentially Reversible Kidney Injury in Heat-Exposed Sugarcane Workers. International Journal of Environmental Research and Public Health. 2020; 17(22):8552.
  1. Ritthirong Pundee, Pornpimol Kongtip, Noppanun Nankongnab, Sirirat Anutrakulchai, Mark Gregory Robson & Susan Woskie. (2020). Cross-shift change of acute kidney injury biomarkers in sugarcane farmers and cutters, Human and Ecological Risk Assessment: An International Journal, DOI: 10.1080/10807039.2020.1812049
  1. Chathuri Rodrigo, Priyantha Nawarathne, Saroj Jayasinghe. (2020). Chronic interstitial nephritis in agricultural communities (CINAC) and lysosomal tubulopathy: Is there a place for anti-oxidants?. Medical Hypotheses, 110414.
  1. Butler-Dawson J, Dally M, Johnson R, J, Johnson E, C, Krisher L, Sánchez-Lozada L, -G, Griffin B, R, Brindley S, Newman L, S. (2020). Association of Copeptin, a Surrogate Marker of Arginine Vasopressin, with Decreased Kidney Function in Sugarcane Workers in Guatemala. Ann Nutr Metab;76:30-36. doi: 10.1159/000506619
  1. Boonruksa P, Maturachon T, Kongtip P, Woskie S. (2020). Heat Stress, Physiological Response, and Heat-Related Symptoms among Thai Sugarcane Workers. International Journal of Environmental Research and Public Health. 17(17):6363.
  1. Gunasekara, T.D.K.S.C.; De Silva, P. M.C.S.; Herath, Chula; Siribaddana, Sisira; Siribaddana, Nipuna; Jayasumana, Channa; Jayasinghe, Sudheera; Cardenas-Gonzalez, Maria; Jayasundara, Nishad. (2020). The Utility of Novel Renal Biomarkers in Assessment of Chronic Kidney Disease of Unknown Etiology (CKDu): A Review. Int. J. Environ. Res. Public Health 17, no. 24: 9522.
  1. Schaeffer, Joshua W.; Adgate, John L.; Reynolds, Stephen J.; Butler-Dawson, Jaime; Krisher, Lyndsay; Dally, Miranda; Johnson, Richard J.; James, Katherine A.; Jaramillo, Diana; Newman, Lee S. 2020. “A Pilot Study to Assess Inhalation Exposures among Sugarcane Workers in Guatemala: Implications for Chronic Kidney Disease of Unknown Origin” Int. J. Environ. Res. Public Health 2020, 17(16), 5708.
  1. Wimalawansa, S. J., Butler M. J., (2020). “Renal tubular lysosomal vacuoles are a generic toxic manifestation and not particularly associated with agrochemicals and heavy metal toxicity or specific to a disease.” Kidney International 97(5): 1058.
  1. Yih, W. K.,  Kulldorff  M., et al. (2019). “Investigating Possible Infectious Causes of Chronic Kidney Disease of Unknown Etiology in a Nicaraguan Mining Community.” Am J Trop Med Hyg. 101(3): 676-683.  DOI: 10.4269 / ajtmh.18-0856
  1. Abraham, G., Agarwal S., et al. (2019). “Chronic Kidney Disease of Unknown Etiology: Hotspots in India and Other Asian Countries.” Semin Nephrol 39(3): 272-277.
  2. Hansson E, Glaser J, Weiss I, Ekström U, Apelqvist J, Hogstedt C, Peraza S, Lucas R, Jakobsson K, Wesseling C, Wegman DH. Workload and cross-harvest kidney injury in a Nicaraguan sugarcane worker cohort. 2019 Occup Environ Med. Nov;76(11):818-826. doi: 10.1136/oemed-2019-105986.
  3. Bullen, A. L., Katz R., et al. (2019). “The SPRINT trial suggests that markers of tubule cell function in the urine associate with risk of subsequent acute kidney injury while injury markers elevate after the injury.” Kidney Int 96(2): 470-479.
  1. Butler-Dawson, J., Krisher L., et al. (2019). “Evaluation of heat stress and cumulative incidence of acute kidney injury in sugarcane workers in Guatemala.” Int Arch Occup Environ Health. 92 ,977 – 990.
  1. Correa-Rotter, R. and R. Garcia-Trabanino (2019). “Mesoamerican Nephropathy.” Semin Nephrol 39(3): 263-271.
  1. Friedman, D. and V. A. Luyckx (2019). “Genetic and Developmental Factors in Chronic Kidney Disease Hotspots.” Semin Nephrol 39(3): 244-255.
  1. Garcia-Garcia, G., Gutiérrez-Padilla A., et al. (2019). “Chronic kidney disease of unknown cause in Mexico: The case of Poncitlan, Jalisco.” Clin Nephrol. 93(1): 42-48.  DOI: 10.5414 / CNP92S107
  1. Gunatilake, S., Seneff S., et al. (2019). “Glyphosate’s Synergistic Toxicity in Combination with Other Factors as a Cause of Chronic Kidney Disease of Unknown Origin.” Int J Environ Res Public Health 16(15). 2734
  1. Herath, N., Dassanyake R., et al. (2019). “Normality data of eGFR and validity of commonly used screening tests for CKD in an area with endemic CKD of unknown etiology; need for age and sex based precise cutoff values.” BMC Nephrol 20(1): 298. DOI: 10.1186 / s12882-019-1477-9
  1. Herrera Valdes, R.,  Almaguer López M., et al. (2019). “Chronic interstitial nephritis of nontraditional causes in Salvadoran agricultural communities.” Clin Nephrol. 93(1): 60-67. doi: 10.5414/CNP92S110
  1. Jayasekara, K. B., Kulasooriya P S., et al. (2019). “Relevance of heat stress and dehydration to chronic kidney disease (CKDu) in Sri Lanka.” Prev Med Rep 15: 100928. doi:  10.1016 / j.pmedr.2019.100928
  1. Jayasinghe, S.,  Lind L., et al. (2019). “DDT and its metabolites could contribute to the aetiology of chronic kidney disease of unknown aetiology (CKDu) and more studies are a priority.” Sci Total Environ 649: 1638-1639. DOI: 10.1016 / j.scitotenv.2018.09.116
  1. Jayasinghe, S. and Y. G. Zhu (2019). “Chronic kidney disease of unknown etiology (CKDu): Using a system dynamics model to conceptualize the multiple environmental causative pathways of the epidemic.” Sci Total Environ 705: 135766. DOI: 10.1016 / j.scitotenv.2019.135766
  1. Jayasumana, C. (2019). “Chronic Interstitial Nephritis in Agricultural Communities (CINAC) in Sri Lanka.” Semin Nephrol 39(3): 278-283.
  1. Johnson, R. J.,  Wesseling C., et al. (2019). “Chronic Kidney Disease of Unknown Cause in Agricultural Communities.” N Engl J Med 380(19): 1843-1852. DOI: 10.1056/NEJMra1813869 
  1. Kulathunga, M.,  Wijayawardena M., et al. (2019). “Chronic kidney disease of unknown aetiology in Sri Lanka and the exposure to environmental chemicals: a review of literature.” Environ Geochem Health. 41 , 2329 – 2338
  1. Lokupathirage, S. M. W.,  Muthusinghe D. S., et al. (2019). “Serological Evidence of Thailand Orthohantavirus or Antigenically Related Virus Infection Among Rodents in a Chronic Kidney Disease of Unknown Etiology Endemic Area, Girandurukotte, Sri Lanka.” Vector Borne Zoonotic Dis. Vol. 19, N ° 11
  1. S, Hamilton; N, Pearce; D, Fecht; P, Vineis. Chronic Kidney Disease of undetermined cause (CKDu), an emerging disease in developing nations: a Malawian geographical study with focus on potable water sources, Environmental Epidemiology: October 2019 – Volume 3 – Issue – p 150. doi: 10.1097/01.EE9.0000607408.99612.32
  1. Mendley, S. R.,  Levin A., et al. (2019). “Chronic kidney diseases in agricultural communities: report from a workshop.” Kidney Int. Vol 96, (5): 1071-1076
  1. Nerbass, F. B. and R. Pecoits-Filho (2019). “Can your work affect your kidney’s health?” Rev Environ Health.  2(6): 998- 1008
  1. Obrador, G. T. and A. Levin (2019). “Introduction: CKD Hotspots.” Semin Nephrol 39(3): 227-229.
  1. O’Callaghan-Gordo, C., et al. (2019). “Prevalence of and risk factors for chronic kidney disease of unknown aetiology in India: secondary data analysis of three population-based cross-sectional studies.” BMJ Open 9(3): e023353. DOI: 10.1136 / bmjopen-2018-023353
  1. Orantes-Navarro, C. M.,  Almaguer-López M., et al. (2019). “The Chronic Kidney Disease Epidemic in El Salvador: A Cross-Sectional Study.” MEDICC Rev 21(2-3): 29-37.
  1. Pinto, U.,  Thoradeniya B., et al. (2019). “Water quality and chronic kidney disease of unknown aetiology (CKDu) in the dry zone region of Sri Lanka: impacts on well-being of village communities and the way forward.” Environ Sci Pollut Res Int. 27 (4): 3892-3907. DOI: 10.1007 / s11356-019-06669-8
  1. Ranasinghe, A. V., et al. (2019). “The incidence, prevalence and trends of Chronic Kidney Disease and Chronic Kidney Disease of uncertain aetiology (CKDu) in the North Central Province of Sri Lanka: an analysis of 30,566 patients.” BMC Nephrol 20(1): 338.
  1. Ruwanpathirana, T.,   Senanayake S., et al. (2019). “Prevalence and risk factors for impaired kidney function in the district of Anuradhapura, Sri Lanka: a cross-sectional population-representative survey in those at risk of chronic kidney disease of unknown aetiology.” BMC Public Health 19(1): 763.
  1. Sarathkumara, Y. D.,  Gamage Ch., et al. (2019). “Exposure to Hantavirus is a Risk Factor Associated with Kidney Diseases in Sri Lanka: A Cross Sectional Study.” Viruses 11(8). DOI: 10.3390 / v11080700
  1. Sato, Y.,  Roncal-Jiménez C. A., et al. (2019). “The increase of core temperature affected the progression of kidney injury by repeated heat stress exposure.” Am J Physiol Renal Physiol. 317 (5): DOI: 10.1152 / ajprenal.00259.2019
  1. Tatapudi, R. R., Rental S., et al. (2019). “High Prevalence of CKD of Unknown Etiology in Uddanam, India.” Kidney Int Rep 4(3): 380-389.
  1. Yoshimatsu, K.,  Gamage C. D., et al. (2019). “Thailand orthohantavirus infection in patients with chronic kidney disease of unknown aetiology in Sri Lanka.” Arch Virol 164(1): 267-271. DOI: 10.1007 / s00705-018-4053-x
  1. Zang, Y.,   Devleesschauwer B., et al. (2019). “Global burden of late-stage chronic kidney d isease resulting from dietary exposure to cadmium, 2015.” Environ Res 169: 72-78. DOI: 10.1016 / j.envres.2018.10.005
  1. Atanda, A., Henry J., et al. (2018). “Hyperuricemia-associated Mesoamerican Nephropathy: Case Report and Review of Literature.” Cureus 10(9): e3282. DOI: 10.7759 / cureus.3282
  1. Aguilar-Ramirez, D., M. Madero (2018). “Untangling Mesoamerican Nephropathy.” Am J Kidney Dis 72(4): 469-471.
  1. Barnett, L. M. A. and B. S. Cummings (2018). “Nephrotoxicity and Renal Pathophysiology: A Contemporary Perspective.” Toxicol Sci 164(2): 379-390.
  1. Dally, M.,  Butler-Dawson  J., et al. (2018). “The impact of heat and impaired kidney function on productivity of Guatemalan sugarcane workers.” PLoS One 13(10): e0205181.
  1. Fischer, R. S. B., Vangala Ch., et al. (2018). “Early detection of acute tubulointerstitial nephritis in the genesis of Mesoamerican nephropathy.” Kidney Int 93(3): 681-690.
  1. Gonzalez-Quiroz, M., et al. (2018). “Decline in Kidney Function among Apparently Healthy Young Adults at Risk of Mesoamerican Nephropathy.” J Am Soc Nephrol.   JASN 29 (8) :2200-2212.
  1. Haas, M. (2018). “Mesoamerican nephropathy: pathology in search of etiology.” Kidney Int 93(3): 538-540.
  1. Herath, C.,  Jayasumana  Ch.,  et al. (2018). “Kidney Diseases in Agricultural Communities: A Case Against Heat-Stress Nephropathy.” Kidney Int Rep 3: 271-280.
  1. Ileperuma, O.,  Weeraratne  S., et al. (2018). “Acronyms, CINAC, ACN, KDUCAL or NUCAL and so on are inappropriate to use for describing CKDu.” J Epidemiol Community Health 72(10): 967-968.
  1. Jayaweera, J. and A. Joseph (2018). “Assessment of healthiness among long term inhabiting army soldiers in dry zone of Sri Lanka.” BMC Res Notes 11(1): 474.
  1. Jha, V. and G. K. Modi (2018). “Getting to know the enemy better-the global burden of chronic kidney disease.” Kidney Int 94(3): 462-464.
  1. Kupferman, J.,  Ramíreaz-Rubio, O., et al. (2018). “Acute Kidney Injury in Sugarcane Workers at Risk for Mesoamerican Nephropathy.” Am J Kidney Dis 72(4): 475-482.
  1. Leite, M. R., Travisan-Zanetta  D. M., et al. (2018). “Sugarcane cutting work, risks, and health effects: a literature review.” Rev Saude Publica 52: 80. doi:  10.11606 / S1518-8787.2018052000138
  1. Levi, M.,  Kjellstrom, T., et al. (2018). “Impact of climate change on occupational health and productivity: a systematic literature review focusing on workplace heat.” Med Lav 109(3): 163-179. doi: 10.23749 / mdl.v109i3.6851
  1. Milagres, T.,  García-Arroyo  F. E., et al. (2018). “Rehydration with fructose worsens dehydration-induced renal damage.” BMC Nephrol 19(1): 180. doi:  10.1186 / s12882-018-0963-9
  1. Nogawa, K., et al. (2018). “Relationship between mortality and rice cadmium concentration in inhabitants of the polluted Jinzu River basin, Toyama, Japan: A 26 year follow-up.” J Appl Toxicol 38(6): 855-861.
  1. Ordunez, P. and W. E. Hoy (2018). “Case definitions and approaches for surveillance of chronic kidney disease in agricultural communities in Central America: policy implications.” Kidney Int 93(2): 284-287.
  1. Ordunez, P.,  Nieto F. J., et al. (2018). “Chronic kidney disease mortality trends in selected Central America countries, 1997-2013: clues to an epidemic of chronic interstitial nephritis of agricultural communities.” J Epidemiol Community Health 72(4): 280-286. DOI: 10.1136 / jech-2017-210023
  1. Roncal-Jimenez, C. A., Sto Y., et al. (2018). “Experimental heat stress nephropathy and liver injury are improved by allopurinol.” Am J Physiol Renal Physiol 315(3): F726-F733. DOI: 10.1152 / ajprenal.00543.2017
  1. Sorensen, C. J., Butler-Dawson  J., et al. (2018). “Risk Factors and Mechanisms Underlying Cross-shift Decline in Kidney Function in Guatemalan Sugarcane Workers.” J Occup Environ Med. Journal of Occupational and Environmental Medicine: Vol 61 (3):239-250  doi:  10.1097 / JOM.0000000000001529
  1. Subramanian, S. and M. M. Javaid (2018). “In Reply to ‘Attempts to Change the Globally Accepted Term, CKDu, to KDUCAL, NUCAL, or CINAC Are Inappropriate’.” Am J Kidney Dis 71(6): 914-915.
  1. Watts, N.,  Amann, M., et al. (2018). “The Lancet Countdown on health and climate change: from 25 years of inaction to a global transformation for public health.” Lancet 391(10120): 581-630.
  1. Wijkstrom, J.,  Jayasumana  Ch., et al. (2018). “Morphological and clinical findings in Sri Lankan patients with chronic kidney disease of unknown cause (CKDu): Similarities and differences with Mesoamerican Nephropathy.” PLoS One 13(3): e0193056.
  1. Wimalawansa, S., Iieperuma O., et al. (2018). “Attempts to Change the Globally Accepted Term, CKDu, to KDUCAL, NUCAL, or CINAC Are Inappropriate.” Am J Kidney Dis 71(6): 914.
  1. Wright, E. M. (2018). “Researchers’ Perceived Challenges in Studying Chronic Kidney Disease of Nontraditional Etiology in Mesoamerica.” MEDICC Rev 20(3): 45-51.
  1. Yoshimatsu, K., Gamage  C. D., et al. (2018). “Thailand orthohantavirus infection in patients with chronic kidney disease of unknown aetiology in Sri Lanka.” Arch Virol. 164 (1): 267-271. DOI: 10.1007 / s00705-018-4053-x
  1. Johnson, R. J. (2017). “Pro: Heat stress as a potential etiology of Mesoamerican and Sri Lankan nephropathy: a late night consult with Sherlock Holmes.” Nephrol Dial Transplant 32(4): 598-602. DOI: 10.1093 / ndt / gfx034
  1. Campese, V. M. (2017). “Con: Mesoamerican nephropathy: is the problem dehydration or rehydration?” Nephrol Dial Transplant 32(4): 603-606.
  1. Fischer, R. S. B.,  Mandayam  S., et al. (2017). “Clinical Evidence of Acute Mesoamerican Nephropathy.” Am J Trop Med Hyg 97(4): 1247-1256.
  1. Gamage, C. D., Yoshimatsu  K., et al. (2017). “Serological evidence of hantavirus infection in Girandurukotte, an area endemic for chronic kidney disease of unknown aetiology (CKDu) in Sri Lanka.” Int J Infect Dis 57: 77-78.
  1. Caplin, B. and D. Nitsch (2017). “Urinary biomarkers of tubular injury in chronic kidney disease.” Kidney Int 91(1): 21-23.
  1. Gonzalez-Quiroz, M., et al. (2017). “Rationale, description and baseline findings of a community-based prospective cohort study of kidney function amongst the young rural population of Northwest Nicaragua.” BMC Nephrol 18(1): 16. DOI: 10.1186 / s12882-016-0422-4
  1. Gonzalez-Quiroz, M., Pearce, N., et al. (2017). “What do epidemiological studies tell us about chronic kidney disease of undetermined cause in Meso-America? A systematic review and meta-analysis.” Clinical Kidney Journal: 1-10.
  1. Grubb, A. (2017). “Cystatin C is Indispensable for Evaluation of Kidney Disease.” EJIFCC 28(4): 268-276.
  1. Hoy, W. and P. Ordunez (2017). Epidemic of Chronic Kidney Disease in Agricultural Communities in Central America. Case definitions, methodological basis and approaches for public health surveillance. Washington, D.C., Pan American Health Organization.  Kidney Int 93(2):284-287.
  1. McTavish, R. K., et al. (2017). “Association Between High Environmental Heat and Risk of Acute Kidney Injury Among Older Adults in a Northern Climate: A Matched Case-Control Study.” Am J Kidney Dis. 71(2):200-208.
  1. Mesnage, R. and M. N. Antoniou (2017). “Facts and Fallacies in the Debate on Glyphosate Toxicity.” Front Public Health 5: 316. doi:  10.3389 / fpubh.2017.00316
  1. Nerbass, F. B.,    Pecoits-Filho  R., et al. (2017). “Occupational Heat Stress and Kidney Health: From Farms to Factories.” Kidney Int Rep 2(6):998-1008. doi:  10.1016 / j.ekir.2017.08.012
  1. Orantes-Navarro, C. M.,  Herrera-Valdés  R., et al. (2017). “Toward a Comprehensive Hypothesis of Chronic Interstitial Nephritis in Agricultural Communities.” Adv Chronic Kidney Dis 24(2): 101-106.
  1. Quinteros, E., Ribó  A., et al. (2017). “Heavy metals and pesticide exposure from agricultural activities and former agrochemical factory in a Salvadoran rural community.” Environ Sci Pollut Res Int 24(2): 1662-1676. DOI: 10.1007 / s11356-016-7899-z
  1. Vandenberg, L. N.,  Blumberg  B., et al. (2017). “Is it time to reassess current safety standards for glyphosate-based herbicides?” J Epidemiol Community Health 71(6): 613-618. DOI: 10.1136 / jech-2016-208463
  1. Wegman, D. H.,   Apelqvist,  J., et al. (2017). “Intervention to diminish dehydration and kidney damage among sugarcane workers.” Scand J Work Environ Health. 44 (1) : 16-24  doi: 10.5271/sjweh.3659
  1. Wijkstrom, J. (2017). CHRONIC KIDNEY DISEASE OF UNKNOWN ETIOLOGY IN CENTRAL AMERICA AND SRI LANKA – RENAL MORPHOLOGY AND CLINICAL CHARACTERISTICS. Department of Clinical Science,  Intervention and Technology (CLINTEC),  Division of Renal Medicine,  Karolinska Institutet. Stockholm, Sweden, Karolinska Institutet. PhD: 63.
  1. Wijkstrom, J.,  González-Quiroz  M., et al. (2017). “Renal Morphology, Clinical Findings, and Progression Rate in Mesoamerican Nephropathy.” Am J Kidney Dis. 69(5): 626-636.
  1. Zoccali, C. (2017). “Causal mechanism and component causes in Mesoamerican-Sri Lankan nephropathy: the moderator’s view.” Nephrol Dial Transplant 32(4): 607-610.
  1. Badurdeen, Z.,  Nanayakkara  N., et al. (2016). “Chronic kidney disease of uncertain etiology in Sri Lanka is a possible sequel of interstitial nephritis!” Clin Nephrol 86 (2016)(13): 106-109. DOI: 10.5414 / CNP86S115
  1. Bodin, T., García-Trabanino R., et al. (2016). “Intervention to reduce heat stress and improve efficiency among sugarcane workers in El Salvador: Phase 1.” Occup Environ Med 73(6): 409-416.
  1. Ferreiro, A.,  Álvarez-Estévez  G., et al. (2016). “Confirmed clinical case of chronic kidney disease of nontraditional causes in agricultural communities in Central America: a case definition for surveillance.” Rev Panam Salud Publica 40(5): 301-308.
  1. Glaser, J.,  Lémery  J., et al. (2016). “Climate Change and the Emergent Epidemic of CKD from Heat Stress in Rural Communities: The Case for Heat Stress Nephropathy.” Clin J Am Soc Nephrol. 11(8):1472-1483.
  1. Kjellstrom, T., et al. (2016). “Heat, Human Performance, and Occupational Health: A Key Issue for the Assessment of Global Climate Change Impacts.” Annu Rev Public Health 37: 97-112. DOI: 10.1146 / annurev-publhealth-032315-021740
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